From 2002 to 2008, reports from the Women’s Health Initiative (WHI) claimed that hormone replacement therapy (HRT) significantly increased the risks of breast cancer development, cardiac events, Alzheimer disease, and stroke. These claims alarmed the public and health professionals alike, causing an almost immediate and sharp decline in the numbers of women receiving HRT. However, the actual data in the published WHI articles reveal that the findings reported in press releases and interviews of the principal investigators were often distorted, oversimplified, or wrong. The current understanding of Menopausal Hormone Therapy shows that the weight of the evidence is clear: women in menopause who have symptoms that seriously affect the quality of their lives should feel secure in taking Hormone Replacement Therapy at the start of menopause and for as many years after as they must to control those symptoms. Any woman worried about her health and longevity should quit smoking before she quits hormones and have routine health screening.